Skip to main content

TABLE 2.

Summary of mitotic chromosome binding datab

E2a No. of cells with:
Total no. of cells %
ON Both OFF No E2
WT 38 9 8 3 58 85
A1 36 5 1 0 42 98
A2 40 0 0 2 42 100
B1 19 1 6 6 32 77
B2 38 1 7 9 55 85
B3 0 0 47 0 47 0
C1 35 8 9 2 54 83
C2 26 14 9 1 50 82
C3 29 5 16 7 57 68
C4 2 2 35 5 44 10
C5 2 0 26 8 36 7
C6 20 18 6 2 46 86
C7 27 8 5 0 40 88
C8 25 9 6 0 40 85
C9 0 0 30 16 46 0
C10 0 0 35 0 35 0
C11 0 0 30 0 30 0
D1 15 13 14 0 42 67
D2 16 10 21 0 47 55
F1 1 15 17 2 35 48
F2 0 3 31 5 39 9
F3 0 0 33 7 40 0
F4 0 0 38 8 46 0
F5 0 0 30 15 45 0
F6 0 0 38 6 44 0
G1 35 10 8 4 57 85
G2 6 0 0 7 13 100
G3 35 9 2 1 47 96
H1 16 9 18 4 47 58
H2 25 13 11 0 49 78
H3 18 23 5 2 48 89
I1 0 0 31 12 43 0
I2 0 0 36 13 49 0
a

Refer to Table 1 for mutations. WT, wild type.

b

Mitotic chromosome binding activity is expressed as ability to bind to mitotic chromosomes. ON, exclusive colocalization with mitotic chromosomes; Both, E2 protein localized both on and off mitotic chromosomes; OFF, exclusion from mitotic chromosomes; No E2, no E2 expression; %, percentage of mitotic cells with E2 bound to mitotic chromosome (ON and Both).