FIG. 4.
Replication profiles of the WT and MSD mutants in Jurkat cells. Viral stocks of the WT and each mutant were prepared from culture supernatant of COS7 cells transfected with proviral DNA, and Jurkat cells were infected with each virus adjusted by the amount of p24. Replication was monitored by measuring the amount of p24 in the culture supernatant at specific time points following infection. A representative result of three independent experiments is shown.