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. 2023 Dec 4;18(12):e0294356. doi: 10.1371/journal.pone.0294356

Table 2. Characteristics about women who have menopausal hormone.

MHT chracteristics Tibolone Combined Estrogen plus progestin by manufacturer Oral Estrogen Combined Estrogen plus progestin by physician Topical estrogen Total MHT
Median duration (months) 25 [11–58] 25 [11–58] 15 [9–40] 16 [9–35] 13 [8–24] 23 [10–55]
Duration (years)
 <5 145,461 (75.5) 97,060 (75.7) 43,376 (82.8) 5,597 (87.1) 1,943 (95.2) 293,437 (76.9)
 5–9.9 34,634 (18) 23,786 (18.6) 6,280 (12) 641 (10) 93 (4.6) 65,434 (17.1)
 ≥10 12,576 (6.5) 7,322 (5.7) 2,748 (5.2) 189 (2.9) 5 (0.2) 22,840 (6)
Duration of previous other MHT (years)
 <5 187,369 (97.2) 126,104 (98.4) 51,635 (98.5) 5,352 (83.3) 2,016 (98.8) 372,476 (97.6)
 5–9.9 4,737 (2.5) 1,895 (1.5) 691 (1.3) 799 (12.4) 24 (1.2) 8,146 (2.1)
 ≥10 565 (0.3) 169 (0.1) 78 (0.1) 276 (4.3) 1 (0) 1,089 (0.3)
Last dosage of Tibolone (per day)
 1.25mg 1,819 (0.9)
 2.5mg 190,658 (99)
 over 5mg 175 (0.1)
Prescribed specialty
 Gynecology 64,852 (33.7) 58,694 (45.8) 21,624 (41.3) 1,532 (23.8) 510 (25) 147,212 (38.6)
 Non-gynecology 127,819 (66.3) 69,474 (54.2) 30,780 (58.7) 4,895 (76.2) 1,531 (75) 234,499 (61.4)

MHT, menopausal hormone therapy

Data are expressed as the number (%) or median [25th percentile, 75th percentile].