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. 2005 Apr;79(8):4908–4917. doi: 10.1128/JVI.79.8.4908-4917.2005

FIG. 1.

FIG. 1.

FIG. 1.

FIG. 1.

FIG. 1.

Survey of HIV-specific IFN-γ-secreting responses in 31 untreated subjects during chronic HIV infection. (A) Location of each stimulatory peptide on a map of the HIV genome. The y axis shows the percentage of individuals recognizing each stimulatory peptide. The sequence of frequently recognized peptides is shown. (B) Cumulative frequency of HIV-specific T-cell responses per million PBMCs for each individual tested. Each stack in the bar represents the number of SFCs/106 PBMCs recognizing separate HIV gene products. The number over each bar is the number of peptides derived from all expressed HIV-1B genes that stimulated above-background levels of IFN-γ secretion. (C) Relative contributions of individual HIV gene products to the cumulative breadth of the HIV-specific response. (D) Relative contributions of individual HIV gene products to the cumulative magnitude of the HIV-specific response.