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Correlation between the magnitude and breadth of HIV-specific responses with rate of CD4+-T-cell decline and plasma viral load among 31 chronically infected individuals. The associations between plasma viral load and cumulative magnitude (A), plasma viral load and cumulative breadth (B), the rate of CD4+-T-cell decline and cumulative magnitude (C), and the rate of CD4+-T-cell decline and cumulative breadth (D) of HIV-specific responses are shown.
