Table 4.
The hazard ratio of categorized lymphocytes and T cells.
| Biomarker |
Level |
Overall | Stable | Aggravated | Hazard ratio (95% CI) | |
|---|---|---|---|---|---|---|
| N | N(%) | N(%) | Unadjusted | Adjusted† | ||
| Lymphocyte count (cells/nL) | ≤1.29 | 150 | 118 (78.7) | 32 (21.3) | Reference | Reference |
| >1.29 | 161 | 151 (93.8) | 10 (6.2) | 0.28 (0.14, 0.57)*** | 0.33 (0.16, 0.68)** | |
| T cell count (cells/mm3) | ≤711 | 44 | 33 (75) | 11 (25) | Reference | Reference |
| >711 | 120 | 111 (92.5) | 9 (7.5) | 0.29 (0.12, 0.7)** | 0.32 (0.13, 0.82)** | |
| CD4+ count (cells/mm3) | ≤409 | 43 | 31 (72.1) | 12 (27.9) | Reference | Reference |
| >409 | 121 | 113 (93.4) | 8 (6.6) | 0.22 (0.09, 0.54)* | 0.24 (0.1, 0.58)** | |
| CD8+ count (cells/mm3) | ≤362 | 85 | 70 (82.4) | 15 (17.6) | Reference | Reference |
| >362 | 79 | 74 (93.7) | 5 (6.3) | 0.34 (0.13, 0.95)* | 0.4 (0.14, 1.14) | |
| T cell (%) | ≤68.4 | 86 | 69 (80.2) | 17 (19.8) | Reference | Reference |
| >68.4 | 78 | 75 (96.2) | 3 (3.8) | 0.19 (0.05, 0.64)** | 0.20 (0.06, 0.68)* | |
| CD4+ (%) | ≤34.7 | 62 | 49 (79) | 13 (21) | Reference | Reference |
| >34.7 | 102 | 95 (93.1) | 7 (6.9) | 0.31 (0.12, 0.77)*** | 0.29 (0.12, 0.73)** | |
| CD8+ (%) | ≤20.2 | 54 | 43 (79.6) | 11 (20.4) | Reference | Reference |
| >20.2 | 110 | 101 (91.8) | 9 (8.2) | 0.39 (0.16, 0.93)* | 0.44 (0.18, 1.1) | |
Adjusted for age.
P < .05.
P < .01.
P < .001.