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. Author manuscript; available in PMC: 2023 Dec 4.
Published in final edited form as: J Glaucoma. 2022 Jun 2;31(9):734–743. doi: 10.1097/IJG.0000000000002055

Table 6:

Summary of Multivariable Linear Models of Structure-Function Relationship of 3×3 mm and 6×6 mm Scan Sizes Optical Coherence Tomography Angiography (OCTA) Superficial Layer Vessel Density and Superficial Spectral Domain OCT Ganglion Cell Complex (GCC) Thickness Measurements with Corresponding Inferior Displaced Visual Field 10–2 Mean Sensitivity.

Scan Size Superficial Vessel Density (%) Superficial? GCC Thickness (μ)
3×3 mm ETDRS Map Estimate (95% CI) p-value Estimate (95% CI) p-value
Para I Hemi (1–3mm) 0.40 (−0.29, 1.08) 0.250 0.34 (0.07, 0.61) 0.014*
Para S Hemi (1–3mm) 0.31 (−0.17, 0.80) 0.194 0.31 (0.16, 0.47) < 0.001***
ParaFovea (1–3mm) 0.48 (−0.02, 0.98) 0.058 0.21 (0.03, 0.40) 0.026*
Whole Image Grid Map
Whole Image I Hemi 0.43 (−0.28, 1.14) 0.224 0.36 (0.09, 0.64) 0.012*
Whole Image S Hemi 0.26 (−0.28, 0.79) 0.334 0.34 (0.17, 0.52) < 0.001***
Whole Image 0.48 (−0.06, 1.01) 0.080 0.21 (0.02, 0.41) 0.036*
6×6mm ETDRS Map
Para I Hemi (1–3mm) 0.84 (0.32, 1.37) 0.002** 0.31 (0.13, 0.50) 0.001**
Para S Hemi (1–3mm) 0.46 (−0.03, 0.94) 0.064 0.36 (0.23, 0.49) < 0.001***
ParaFovea (1–3mm) 0.65 (0.21, 1.08) 0.004** 0.27 (0.14, 0.41) < 0.001***
Peri I Hemi (3–6mm) 0.87 (0.22, 1.52) 0.010** 0.19 (−0.07, 0.46) 0.149
Peri S Hemi (3–6mm) 0.53 (−0.16, 1.22) 0.127 0.27 (0.05, 0.50) 0.020*
PeriFovea (3–6mm) 0.63 (0.08, 1.19) 0.027* 0.10 (−0.11, 0.32) 0.335
All I Hemi (1–6mm) 0.93 (0.30, 1.56) 0.005** 0.22 (−0.03, 0.46) 0.079
All S Hemi (1–6mm) 0.54 (−0.12, 1.20) 0.108 0.31 (0.11, 0.51) 0.004**
All (1–6mm) 0.67 (0.13, 1.21) 0.016* 0.16 (−0.04, 0.35) 0.113
Whole Image Grid Map
Whole Image I Hemi 0.92 (0.27, 1.56) 0.007** 0.23 (−0.02, 0.49) 0.073
Whole Image S Hemi 0.49 (−0.18, 1.17) 0.149 0.34 (0.12, 0.56) 0.003**
Whole Image 0.62 (0.07, 1.18) 0.029* 0.17 (−0.05, 0.38) 0.122
*

Multivariable estimates are adjusted for GCC thickness, patient age, and the scan quality index.

S: Superior, I: Inferior. Hemi: Hemifield. Consider Figures 1 and 2 for better correspondence of each region.