TABLE 3.
Characterization of E57 and EJB escape virusesa
| Virus | Amino acid no. | Amino acid change | Codon change |
|---|---|---|---|
| E57A2 | 229 | G to E | GGA to GAA |
| E57A3 | 20 | H to Q | CAC to CAA |
| 226 | K to E | AAG to GAG | |
| E57B1, E57B3 | 226 | K to E | AAG to GAG |
| E57B2, E57C3 | 226 | K to N | AAG to AAT |
| EJB2B, 2C, 2F | 182 | N to D | AAT to GAT |
| 229 | G to E | GGA to GAA | |
| 231 | L to P | CTT to CCT | |
| EJB2D, 2E, 3F | 182 | N to D | AAT to GAT |
| 231 | L to P | CTT to CCT |
a
Amino acid numbering is from the mature protein minus the signal peptide. Wild-type CVS-11 sequence was determined in a similar fashion from the original virus stock used to generate the escape viruses.