Table 2.

Case reports of distant recurrent breast cancer metastases.

Case	Clinical presentation	Interval
Xiao L. et al[2]	The patient had modified radical surgery mastectomy for right-sided breast cancer in 1991 and received 4 cycles of chemotherapy and tamoxifen for 5 yr after surgery. 2015, she presented with “facial edema and chest distress” and received 18F-FDG-PET/CT, which suggested increased FDG uptake in the right supraclavicular lymph nodes, mediastinum and sternum, and after biopsy, suggested Immunohistochemistry confirmed strong positive ER and PR and positive HER2, and local recurrence of breast cancer was considered.	24 yr
Tashima Y. et al[3]	The patient underwent radical surgery for left-sided breast cancer in 1975. 2014, she was seen for lymphedema of the left upper extremity, CT showed soft tissue growth on the left chest wall, and an invasive breast cancer was suggested by biopsy. immunohistochemistry confirmed strong positive ER and PR and negative HER2. Local recurrence of breast cancer was considered.	39 yr
Kusama M. et al[4]	The patient underwent modified radical mastectomy for left-sided breast cancer in 1984 and was seen in 2000 for dyspnea, which, in combination with chest CT, suggested pleural metastases.	16 yr
Igarashi T. et al[5]	The patient underwent a modified radical mastectomy for breast cancer in 1970, with a case suggestive of a scirrhous carcinoma, and was seen in 1994 for a chest wall tumor, with a recurrence of breast cancer confirmed after puncture.	24 yr