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. 2023 Dec 1;102(48):e36353. doi: 10.1097/MD.0000000000036353

Table 2.

The relationship between hsa_circ_0124554 expression (2-ΔΔCt) and clinicopathological features in colorectal cancer patients.

Clinicopathological factor No of cases Hsa_circ_0124554 expression level P value
High(%) Low(%)
All cases 40 20 (50.0) 20 (50.0)
Age (yr) >.999
 <60 9 4 (44.4) 5 (55.6)
 ≥60 31 16 (51.6) 15 (48.4)
Gender .744
 Male 25 13 (52.0) 12 (48.0)
 Female 15 7 (46.7) 8 (53.3)
Diameter(cm) .337
 ≥5 17 7 (41.2) 10 (58.8)
 <5 23 13 (56.5) 10 (43.5)
Differentiation .001
 Well and moderate 29 10 (34.5) 19 (65.5)
 Poor 11 10 (90.9) 1 (9.1)
Lymphatic metastasis .752
 Positive 19 10 (52.6) 9 (47.4)
 Negative 21 10 (47.6) 11 (52.4)
Lymphovascular invasion .057
 Present 18 12 (66.7) 6 (33.3)
 Absent 22 8 (36.4) 14 (63.6)
Perineural invasion .018
 Present 13 10 (76.9) 3 (23.1)
 Absent 27 10 (37.0) 17 (63.0)
Distant metastasis .487
 M0 38 18 (47.4) 20 (52.6)
 M1 2 2 (100.0) 0 (0)
Invasion .044
 Tis-T2 8 1 (12.5) 7 (87.5)
 T3-T4 32 19 (59.4) 13 (40.6)
TNM stage .525
 0-II 22 10 (45.5) 12 (54.5)
 III-IV 18 10 (55.6) 8 (44.4)
Primary tumor site .519
 Colon 24 11 (45.8) 13 (54.2)
 Rectum 16 9 (56.3) 7 (43.8)
CEA in μg/L >.999
 ≥5 18 9 (50.0) 9 (50.0)
 <5 22 11 (50.0) 11 (50.0)
CA19-9 in U/mL >.999
 ≥25 10 5 (50.0) 5 (50.0)
 <25 30 15 (50.0) 15 (50.0)

The bold symbol means statistical significance.

CA19-9 = carbohydrate antigen 19-9, CEA = carcinoembryonic antigen, TNM = tumor node metastasis.