Table 2.

Number and percentage of genes in sequenced exDNA from exhausted media of different fedbatch conditions (EFC and LFC at the end of the runs and EFC at 6h) compared to eccDNA [33].

The percentages refer to genes included in specific KEGG metabolic pathways either exclusively associated to respiratory metabolism (TCA cycle, pentose phosphate, oxidative phosphorylation) or common to both fermentative and respiratory metabolism (glucose pathways and cell cycle).

	Genes in exDNA	TCA cycle		Pentose phosphate		Oxidative phosphorylation		Glycolysis / gluconeogenesis		Cell cycle
Genes in KEGG pathway		31		28		76		55		130
EFC	1001	2	6%	3	11%	0	0%	10	18%	24	18%
EFC_6h	1823	7	23%	11	39%	2	3%	17	31%	45	35%
LFC	4632	22	71%	23	82%	4	5%	40	73%	101	78%
eccDNA	1861	16	52%	10	36%	2	3%	0	0%	42	32%