FIG. 2.

Emergence of peptide-resistant virus. P0 shows virus growth in the absence of peptide. P1 shows growth of the culture in the presence of 300 nM N44*. P2 was initiated from supernatant from the P1 culture and shows growth in the presence of 600 nM N44*. P3 was initiated from supernatant from the P2 culture and shows growth in the presence of 600 nM N44*. P4 was initiated from supernatant from the P3 culture and shows growth in the presence of 1,200 nM N44*.