Table 3. Logistic regression results for risk of rosacea, when acid suppressants use was limited for 1 year.

Variables		Unadjusted			Adjusteda
		OR	95% CI	P value	OR	95% CI	P value
cDDD
	None	1.00	Reference		1.00	Reference
	< 10	1.62	1.32–2.00	< 0.001	1.53	1.24–1.90	< 0.001
	10–30	1.91	1.50–2.44	< 0.001	1.76	1.37–2.27	< 0.001
	> 30	2.27	1.76–2.92	< 0.001	2.05	1.56–2.69	< 0.001
Residence
	Urban	1.00	Reference		1.00	Reference
	Rural	2.58	2.18–3.06	< 0.001	2.67	2.24–3.19	< 0.001
CCI score
	0	1.00	Reference		1.00	Reference
	1	1.37	1.15–1.83	0.007	1.30	1.01–1.66	0.040
	≥ 2	1.45	1.15–1.83	0.002	1.43	1.09–1.86	0.009
Comorbidities
	Hypertension	1.07	0.70–1.64	0.760	0.95	0.61–1.49	0.800
	DM	0.91	0.69–1.21	0.530	0.78	0.57–1.05	0.100
	Malignancy	0.67	0.44–1.00	0.051	0.54	0.34–0.85	0.008
	Auto-immune disease	2.68	0.95–7.56	0.060	1.77	0.60–5.22	0.300
	Thyroid disease	1.86	1.35–2.56	< 0.001	1.83	1.30–2.56	< 0.001
	Depression	1.80	1.24–2.61	0.002	1.59	1.08–2.34	0.020
	Migraine	1.47	0.79–2.39	0.270	1.04	0.58–1.86	0.910

CCI = Charlson Comorbidity Index, cDDD = cumulative defined daily dose, CI = confidence interval, DM = diabetes mellitus, OR = odds ratio.

^aAdjusted for residence, CCI, and comorbidities.