Table 1.
DrugBank-based hub genes-associated drugs
| Sr. No | Hub gene | Drug name | Effect | Reference | Group |
|---|---|---|---|---|---|
| 1 | CCL25 | Methotrexate | Decrease expression of CCL25 mRNA | A23201 | Approved |
| Acetylcysteine | A20451 | ||||
| 2 | CXCL10 | Acetaminophen | Decrease expression of CXCL10 mRNA | A20426 | Approved |
| Acteoside | A20456 | ||||
| Cyclosporine | A20661 | ||||
| Polydatin | A20456 | ||||
| 3 | CXCL12 | Belinostat | Increase expression of CXCL12 mRNA | A21037 | Approved |
| Decitabine | A21958 | ||||
| Mestranol | A21106 | ||||
| 4 | CXCL16 | Cyclosporine | Decrease expression of CXCL16 mRNA | A20661 | Approved |
| Estradiol | A21424 |
CXCL10 = C-X-C motif chemokine ligand 10, CXCL12 = C-X-C motif chemokine ligand 12, CXCL16 = C-X-C motif chemokine ligand 16, CCL25 = CC motif chemokine ligand 25.