Table 1.
Baseline characteristics in MSKCC and TCGA cohorts
| Characteristics | MSKCC cohort | TCGA cohort |
|---|---|---|
| Age, n (%) | ||
| ≤ 60 | 71 (65%) | 174 (35%) |
| > 60 | 38 (35%) | 329 (65%) |
| Sex, n (%) | ||
| Female | 48 (44%) | 237 (47%) |
| Male | 61 (56%) | 266 (53%) |
| Cancer type, n (%) | ||
| Colon Adenocarcinoma | 87 (80%) | 318 (63%) |
| Rectal Adenocarcinoma | 16 (15%) | 131 (26%) |
| Mucinous Adenocarcinoma of the Colon and Rectum | 4 (4%) | 53 (11%) |
| Signet Ring Cell Adenocarcinoma of the Colon and Rectum | 4 (4%) | 0 |
| Colorectal Adenocarcinoma | 1 (1%) | 0 |
| Drug type, n (%) | ||
| Combo | 10 (9.1%) | / |
| CTLA4 | 1 (0.9%) | / |
| PD-1/PDL-1 | 98 (90%) | / |
| Gene, n (%) | ||
| RNF43 mutation | 21 (19%) | 45 (9%) |
| RNF43 wild-type | 88 (81%) | 458 (91%) |
| Sample type, n (%) | ||
| Metastasis | 59 (54%) | 0 |
| Primary | 50 (46%) | 503 (100%) |