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. 2023 Nov 15;13(11):5254–5270.

Figure 2.

Figure 2

Co-culture with LX-2 results in elevated expression of PRDM16 in HCC cells. A. Analysis of transcriptome changes in HCC cells caused by co-cultured with LX-2 in the GSE193660 dataset. B. Differentially expressed transcription factors in HCC cells resulting from co-cultured with LX-2. C. TCF23 and PRDM16 expression in HCC patients predicted in the UALCAN database. D. The prognostic significance of PRDM16 expression on the survival of HCC patients was analyzed by the UALCAN database. E. PRDM16 mRNA expression in HCC cells after co-culture with LX-2 in the presence or absence of GW4869 was measured using RT-qPCR. The results represent means ± SD, *P < 0.05 vs Co-Culture (-); #P < 0.05 vs Co-Culture (+) + DMSO. All experiments were repeated at least three times, two-way ANOVA.