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. 2023 Nov 15;13(11):5254–5270.

Figure 6.

Figure 6

Tangeretin reverses the promoting effect of LX-2-derived EVs on HCC cell malignant phenotype. A. The effect of Tangeretin on Notch signaling pathway- and EMT-related protein expression in HCC cells. B. The migratory activity of HCC cells after Tangeretin treatment was measured using Transwell assay. C. The invasive activity of HCC cells after Tangeretin treatment was measured using a Transwell assay. D. The proliferative activity of HCC cells after Tangeretin treatment was measured using CCK8. E. EdU+ cells in HCC cells after Tangeretin treatment were measured using EdU staining. The results represent means ± SD, *P < 0.05 vs EVs-NC + DMSO. All experiments were repeated at least three times, two-way ANOVA.