Table 1.
Biometric and biochemical analysis
| Normal salt | High salt | |
|---|---|---|
| n | 8 | 7 |
| sBP (mm Hg) | 147.2 ± 3.2 | 171.3 ± 6.8* |
| HR (beats/min) | 409.0 ± 6.2 | 416.0 ± 9.4 |
| BW (mg) | 268.9 ± 13.2 | 278.3 ± 9.1 |
| Heart (mg/g BW) | 3.72 ± 0.06 | 4.16 ± 0.15* |
| Kidneya | ||
| Right (mg/g BW) | 4.22 ± 0.10 | 5.23 ± 0.21† |
| Left (mg/g BW) | 3.99 ± 0.06 | 5.14 ± 0.18† |
| Serum | ||
| TP (g/dL) | 5.61 ± 0.11 | 5.40 ± 0.18 |
| Alb (g/dL) | 3.83 ± 0.07 | 3.49 ± 0.12 |
| BUN (mg/dL) | 20.0 ± 0.8 | 21.7 ± 1.3 |
| Cr (mg/dL) | 0.34 ± 0.03 | 0.32 ± 0.04 |
| UA (mg/dL) | 0.69 ± 0.17 | 1.37 ± 0.64 |
| Na (mEq/L) | 136.5 ± 0.8 | 135.3 ± 0.7 |
| K (mEq/L) | 4.71 ± 0.25 | 5.10 ± 0.40 |
| Cl (mEq/L) | 99.6 ± 0.7 | 97.4 ± 0.9 |
| Ca (mEq/L) | 10.2 ± 0.1 | 10.1 ± 0.2 |
| IP (mg/dL) | 10.1 ± 0.7 | 10.1 ± 0.8 |
| T-Cho (mg/dL) | 70.4 ± 3.7 | 87.6 ± 4.5 |
sBP systolic blood pressure; HR heart rate; BW body weight; TP total protein; Alb albumin; BUN blood urea nitrogen; Cr creatinine; UA uric acid; Na sodium; K potassium; Cl chloride; Ca calcium; IP inorganic phosphate; T-Cho total cholesterol. Values are mean ± SEM. *P < 0.05 vs DahlS rats fed normal salt by unpaired t-test
aOne-way analysis of variance (ANOVA) followed by Tukey’s honestly significant difference test was used to compare kidney weights. †P < 0.05 vs the same side kidney of DahlS rats fed normal salt by Tukey’s honestly significant difference test