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. 2023 Oct 21;29(11):2737–2741. doi: 10.1038/s41591-023-02605-z

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© The Author(s) 2023, corrected publication 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Extended Data Fig. 4 — Promoter H3K4me3 signal is shown at selected genes across N = 202 biologically independent plasma samples stratified by cancer type. Orange indicates cancer types in which the indicated gene is expected to be expressed. Wilcoxon two-sided p-values are indicated for comparison of samples in which expression is expected versus all other samples. For NECTIN4 and ERBB3, signal is compared between healthy volunteer plasma and cancer patient plasma because these genes are expressed across various cancer types. Signal at GAPDH is shown as a control. Lower, middle, and upper hinges indicate 25^th, 50^th, and 75^th percentiles; whiskers extend to 1.5 x the inter-quartile ranges (IQR).