Table 3.
Correlation of ROR2 and Wnt5a expression with clinicopathologic characteristics
| ROR2 and Wnt5a expression | P value | ||||
|---|---|---|---|---|---|
| ROR2+Wnt5a+ (n = 46) | ROR2+Wnt5a– (n = 17) | ROR2-Wnt5a+ (n = 101) | ROR2-Wnt5a– (n = 79) | ||
| Sex | |||||
| Male | 41 | 14 | 85 | 60 | 0.272 |
| Female | 5 | 3 | 16 | 19 | |
| Age (years) | |||||
| ≤ 60 | 20 | 9 | 42 | 31 | 0.770 |
| > 60 | 26 | 8 | 59 | 48 | |
| HBV | |||||
| Negative | 26 | 9 | 63 | 47 | 0.845 |
| Positive | 20 | 8 | 38 | 32 | |
| HCV | |||||
| Negative | 34 | 12 | 57 | 40 | 0.052 |
| Positive | 12 | 5 | 44 | 39 | |
| AFP (ng/ml) | |||||
| ≤ 10 | 29 | 11 | 59 | 28 | 0.006a |
| > 10 | 17 | 6 | 42 | 49 | |
| PIVKAII (mAU/ml) | |||||
| ≤ 40 | 17 | 7 | 43 | 34 | 0.940 |
| > 40 | 27 | 10 | 56 | 43 | |
| Differentiation | |||||
| Well-moderate | 43 | 16 | 82 | 53 | 0.001a |
| Poor | 3 | 1 | 19 | 26 | |
| Tumor number | |||||
| One | 34 | 12 | 78 | 63 | 0.806 |
| Multiple | 12 | 5 | 23 | 16 | |
| Tumor size (cm) | |||||
| ≤ 5 | 31 | 9 | 70 | 55 | 0.583 |
| > 5 | 15 | 8 | 31 | 24 | |
| Vascular invasion | |||||
| Negative | 43 | 15 | 81 | 65 | 0.208 |
| Positive | 3 | 2 | 20 | 14 | |
| Non-cancerous liver | |||||
| No cirrhosis | 30 | 9 | 65 | 53 | 0.705 |
| Cirrhosis | 16 | 8 | 36 | 26 | |
HBV hepatitis B virus, HCV hepatitis C virus, AFP α-fetoprotein, PIVKAII protein induced by vitamin K absence or antagonist II
aP < 0.05