Table 3.
Multivariable analysis of predictors for PHLF (ISGLS grade B/C)
| Univariable analysis | Multivariable analysis | |||||
|---|---|---|---|---|---|---|
| OR | 95% CI | p value | OR | 95% CI | p value | |
| Age ≥65 years | 1.40 | 0.81–2.41 | 0.228 | |||
| Male sex | 1.54 | 0.85–2.77 | 0.152 | |||
| BMI ≥ 25 kg/m2 | 1.08 | 0.62–1.89 | 0.788 | |||
| ASA score | ||||||
| I/II | Ref | – | – | |||
| III/IV | 1.29 | 0.74–2.26 | 0.366 | |||
| Jaundice at presentation | ||||||
| Biliary drainage | 2.86 | 1.26–6.52 | 0.012 | |||
| Any | 4.00 | 1.21–13.21 | 0.023 | |||
| Preoperative cholangitis | 2.39 | 1.38–4.13 | 0.002 | 2.38 | 1.36–4.17 | 0.002 |
| FLR below 40% | 2.71 | 1.52–4.82 | <0.001 | 2.40 | 1.31–4.38 | 0.005 |
| PV reconstruction | 0.79 | 0.46–1.36 | 0.395 | |||
| HA reconstruction | 1.55 | 0.49–4.89 | 0.450 | |||
| Hepatic steatosis | ||||||
| Grade 0 (< 5 %) | Ref | – | – | Ref | – | – |
| Grades 1–3 (≥ 5 %) | 1.36 | 0.69–2.68 | 0.370 | 1.36 | 0.67–2.73 | 0.395 |
| Hepatic fibrosis | ||||||
| None | Ref | – | – | Ref | – | – |
| Fibrosisa | 0.76 | 0.41–1.41 | 0.383 | 0.76 | 0.40–1.45 | 0.408 |
PHLF posthepatectomy liver failure, ISGLS International Study Group of Liver Surgery, OR odds ratio, CI confidence interval, BMI body mass index, ASA American Society of Anesthesiologists, FLR future liver remnant, PV portal vein, HA hepatic artery
aPeriportal fibrosis, septal fibrosis, or biliary cirrhosis