TABLE 1.

3C PCR primers and probes used in this study

Primer or probe	Sequence(s)
Primers for 3C assays
MfeI digestion
1	5′ CAA CCA GTA TTG AGA GAC TC 3′
2	5′ TCA GAG GAC TGC CCA CTA TC 3′
3	5′ CCA CAA GGA ATC CTG CAG 3′
4	5′ TAG GTA TGT GTC CCA CTG TC 3′
5	5′ ACA GGT GAA GAA GCA GAA CTG 3′
6	5′ CTC TCC ACA GTC TCC ATC G 3′
7	5′ ATC CTT AGG TAC ATA GAC AC 3′
NspI digestion
Porphobilinogen
deaminase	5′ GTG GGT GGT GGA GGT AAG GT 3′, 5′ GGT GCA CTT GGT GAA AGA AGA G 3′
Vκ21-5	5′ ACA GAC ACA CTC CTG CTA TA 3′
8	5′ TGA AAT GCA TCA CAC CAG C 3′
9	5′ CGT CTT AGG CTT CTG AGA CC 3′
10	5′ CAG TCC TTT CTA AGG TTC ACG 3′
11	5′ CTA ATA GTC CCA TGC TCT CC 3′
12	5′ TAT CCA TTC CTC TGT TGA GG 3′
13	5′ CCC AAT GCT TTT GCA CAG TC 3′
14	5′ GGA ATG AGG TTG TGT GTT GC 3′
15	5′ CTA ACT TAG ACC AGG AGA CC 3′
16	5′ TGC CAG TGA GTG TAG TGA CC 3′
17	5′ TGT CAG CTT GCC AAG TAG AC 3′
18	5′ CAA ACA AGA GAC CCT CTC TC 3′
19	5′ CTA ACA AAC CAC ACT TCT GG 3′
20	5′ TCT GCA TCG CAC ACT GTC C 3′
21	5′ TCC TGG GTT GTG TCT GTG G 3′
22	5′ ATA CCA ACA GCC GAG GGA G 3′
23	5′ ATG TGG AGG CAC AGA CAG G 3′
AseI digestion
24	5′ TCT GTT GAG ATG CCA ACT C 3′
25	5′ GTT TCC ATC TTG CTA CCT C 3′
26	5′ AAA GAA TAC AGC ATG TGA C 3′
27	5′ CAA AAT TTG AGG TCA TTG GG 3′
28	5′ GGA GTC TGC TGT CCT TAC AGG 3′
Probes for Southern blots
MfeI digestion
Ei	5′ ACT GGA TAC AAC CAA AAT GTC CAC CAA 3′
E3′	5′ ACA CAT TTA GCA ATG TAA CAG G 3′
Ed	5′ CAT AGC ACG GTA GAA TCA AGA GAG CCT G 3′
NspI digestion
Ei	5′ CCA TGG TAG GTT TGA GGA GGC ATA CTT CC 3′
E3′	5′ TCA GTA TCC TTG AAG AGT TCT GAT ATG GTC 3′
Ed	5′ CAC ACA CAC ACA CAC AAC TTC GAA AAG ACA 3′
Ed for downstream
border	5′ AAC AGC TCC TAG GGA AGG ATC AAA GGA AGG 3′
AseI digestion	5′ GGC TGC TCA TAA TTC TAT TGT TTT TCT TGG 3′