Table 2.
Baseline characteristics of participants (N = 2398).
| Characteristic | Hyperhomocysteinemia (HHCY) | P value | |
|---|---|---|---|
| No | Yes | ||
| N | 2370 | 28 | |
| Age (year) | 32.16 (31.35, 32.96) | 41.14 (38.67, 43.60) | < 0.0001 |
| BMI (kg/m^2) | 27.47 (27.01, 27.93) | 27.68 (24.02, 31.34) | 0.9102 |
| Homocysteine (μmol/L) | 6.82 (6.70, 6.94) | 20.68 (16.24, 25.11) | < 0.0001 |
| folate, rbc (ng/ml rbc) | 273.78 (265.21, 282.35) | 223.30 (189.85, 256.75) | 0.0109 |
| vitamin b12, serum (pg/ml) | 511.56 (476.33, 546.79) | 357.71 (287.67, 427.76) | 0.0007 |
| folate, serum (ng/ml) | 13.27 (12.57, 13.97) | 6.00 (3.92, 8.09) | < 0.0001 |
| ferritin (ng/ml) | 55.61 (52.33, 58.89) | 169.75 (74.49, 265.01) | 0.0266 |
| segmented neutrophils percent (%) | 59.90 (59.43, 60.37) | 64.05 (56.84, 71.26) | 0.2665 |
| segmented neutrophils number | 4.61 (4.54, 4.68) | 4.97 (3.91, 6.03) | 0.5186 |
| Race | 0.9581 | ||
| Mexican American | 9.39 (6.98, 12.51) | 7.05 (2.07, 21.41) | |
| Other hispanic | 5.70 (3.82, 8.42) | 3.69 (0.31, 32.17) | |
| Non-hispanic white | 65.90 (60.70, 70.74) | 66.95 (40.06, 86.00) | |
| Non-hispanic black | 14.09 (11.19, 17.59) | 15.59 (5.40, 37.40) | |
| Other race—including multi-racial | 4.93 (3.64, 6.65) | 6.72 (0.83, 38.33) | |
| Education level | 0.3660 | ||
| < High school | 25.14 (22.42, 28.08) | 34.77 (12.33, 66.89) | |
| High school | 21.84 (20.16, 23.63) | 29.88 (9.52, 63.32) | |
| > High school | 53.01 (50.07, 55.93) | 35.34 (15.62, 61.76) | |
| Bacterial Vaginosis | 0.0006 | ||
| Negative | 61.18 (58.51, 63.78) | 25.83 (9.75, 52.90) | |
| Positive | 38.82 (36.22, 41.49) | 74.17 (47.10, 90.25) | |
*BMI was calculated as the body weight in kilograms divided by the square of the height in meters;
HHCY: HCY concentration in plasma > 15 μmol/L.
Data in the Table 2, for continuous variables: survey-weighted mean (95% CI), P value was by survey-weighted linear regression (svyglm) ; for categorical variables: survey-weighted percentage (95% CI), P value was by survey-weighted Chi-square test (svytable).