Table 3.
Significant correlation of urinary exosomal miRNA with baseline parameters of IgA nephropathy cases.
| Clinical parameter | miRNA | Pearson correlation | P value | Adjusted P value for age |
|---|---|---|---|---|
| Age | hsa-miR-491-3p | 0.772496182 | 6.04609E-06 | 0.043423004 |
| egfr | hsa-miR-375 | − 0.54406 | 0.004933 | |
| hsa-miR-31-5p | − 0.51072 | 0.009087 | ||
| hsa-miR-664b-5p | − 0.49217 | 0.01245 | ||
| hsa-miR-141-3p | − 0.46921 | 0.017971 | ||
| hsa-miR-200c-3p | − 0.43995 | 0.027755 | ||
| hsa-miR-379-5p | 0.412962 | 0.040198 | ||
| hsa-miR-378 h | 0.4311 | 0.031435 | ||
| hsa-miR-548n | 0.435125 | 0.029715 | ||
| hsa-miR-503-3p | 0.457449 | 0.021494 | ||
| hsa-miR-769-3p | 0.476456 | 0.016047 | ||
| hsa-miR-1288-3p | 0.490151 | 0.01287 | ||
| hsa-miR-320e | 0.495641 | 0.011752 | ||
| hsa-miR-548z + hsa-miR-548 h-3p | 0.498938 | 0.01112 | ||
| hsa-miR-877-5p | 0.502804 | 0.010415 | ||
| hsa-miR-888-5p | 0.514417 | 0.008516 | ||
| S. creatinine | hsa-miR-548q | − 0.48525 | 0.013942 | |
| hsa-miR-378 h | − 0.46509 | 0.019149 | ||
| hsa-miR-1306-3p | − 0.44899 | 0.024358 | ||
| hsa-miR-1288-3p | − 0.43612 | 0.029302 | ||
| hsa-miR-5010-5p | − 0.43251 | 0.030824 | ||
| hsa-miR-3918 | − 0.41029 | 0.041637 | ||
| hsa-miR-641 | − 0.40747 | 0.043204 | ||
| hsa-miR-200b-3p | 0.424832 | 0.034271 | ||
| hsa-miR-612 | 0.460265 | 0.020604 | ||
| hsa-miR-375 | 0.527563 | 0.006724 | ||
| 24 h urine protein | hsa-miR-22-3p | − 0.49976 | 0.010966 | |
| hsa-let-7 g-5p | − 0.45284 | 0.02302 | ||
| hsa-miR-664b-5p | − 0.44754 | 0.024878 | ||
| hsa-miR-362-3p | − 0.44636 | 0.025308 | ||
| hsa-miR-10b-5p | − 0.4404 | 0.027577 | ||
| hsa-miR-100-5p | − 0.41117 | 0.041161 | ||
| hsa-miR-31-5p | − 0.40368 | 0.045375 | ||
| hsa-miR-23a-3p | − 0.40259 | 0.046015 | ||
| hsa-miR-222-3p | − 0.40199 | 0.046375 | ||
| hsa-miR-502-5p | 0.454568 | 0.022437 | ||
| hsa-miR-1285-5p | 0.458466 | 0.021169 | ||
| hsa-miR-4284 | 0.476136 | 0.016128 | ||
| hsa-miR-206 | 0.480491 | 0.015051 | ||
| hsa-miR-888-5p | 0.492791 | 0.012322 | ||
| hsa-miR-548ar-5p | 0.506437 | 0.009787 | ||
| hsa-miR-2117 | 0.516496 | 0.008209 | ||
| hsa-miR-1972 | 0.518825 | 0.007876 | ||
| hsa-miR-664b-3p | 0.633966 | 0.000667 | ||
| hsa-miR-1286 | 0.647801 | 0.000463 | ||
| Mesangial expansion | hsa-miR-1276 | − 0.554350538 | 0.004033 | |
| hsa-miR-148b-3p | − 0.54655137 | 0.0047 | ||
| hsa-miR-4286 | − 0.50720338 | 0.009658 | ||
| hsa-miR-3161 | − 0.474829522 | 0.016464 | ||
| hsa-miR-549a | − 0.467379209 | 0.018487 | ||
| hsa-miR-2116-5p | − 0.415819383 | 0.038703 | ||
| hsa-miR-617 | 0.50912478 | 0.009342 | ||
| hsa-miR-370-3p | 0.513116038 | 0.008713 | ||
| hsa-miR-939-5p | 0.520636112 | 0.007624 | ||
| hsa-miR-95-3p | 0.533631587 | 0.00601 | ||
| hsa-miR-145-5p | 0.558133594 | 0.003739 | ||
| hsa-miR-552-3p | 0.564853874 | 0.003262 | ||
| hsa-miR-1268a | 0.567029713 | 0.003119 | ||
| hsa-miR-376b-3p | 0.601323816 | 0.001476 | ||
| hsa-miR-345-5p | 0.640731043 | 0.000559 | ||
| hsa-miR-936 | 0.660839044 | 0.000323 | ||
| Endocapillary proliferation | hsa-miR-141-3p | − 0.585538186 | 0.002104 | |
| hsa-miR-128–1-5p | − 0.552425255 | 0.00419 | ||
| hsa-miR-765 | − 0.55039623 | 0.004361 | ||
| hsa-miR-378e | − 0.520373969 | 0.00766 | ||
| hsa-miR-21-5p | − 0.515984397 | 0.008284 | ||
| hsa-miR-15a-5p | − 0.515499378 | 0.008355 | ||
| hsa-miR-204-5p | − 0.504783483 | 0.010069 | ||
| hsa-miR-1246 | − 0.501959962 | 0.010566 | ||
| hsa-miR-548q | − 0.497589026 | 0.011375 | ||
| hsa-miR-99a-5p | − 0.480267763 | 0.015105 | ||
| hsa-miR-450b-5p | 0.59814067 | 0.001588 | ||
| hsa-miR-597-5p | 0.601822556 | 0.001459 | ||
| hsa-miR-450a-1-3p | 0.615619987 | 0.001053 | ||
| hsa-miR-384 | 0.623321915 | 0.000873 | ||
| hsa-miR-523-3p | 0.633910168 | 0.000668 | ||
| hsa-miR-502-5p | 0.652513084 | 0.000408 | ||
| hsa-miR-1247-5p | 0.654903136 | 0.000382 | ||
| hsa-miR-133a-5p | 0.661072747 | 0.000321 | ||
| hsa-miR-382-5p | 0.687505183 | 0.000146 | ||
| hsa-miR-548d-3p | 0.697247218 | 0.000107 | ||
| Glomerulosclerosis | hsa-miR-3918 | − 0.440159559 | 0.02767 | |
| hsa-miR-1178-3p | − 0.428758656 | 0.032471 | ||
| hsa-miR-25-3p | 0.397451159 | 0.049134 | ||
| hsa-miR-93-5p | 0.432557742 | 0.030803 | ||
| hsa-miR-601 | 0.47677605 | 0.015966 | ||
| hsa-miR-4488 | 0.488926714 | 0.013131 | ||
| hsa-miR-423-3p | 0.50991998 | 0.009214 | ||
| Interstitial fibrosis and tubular atrophy | hsa-miR-1258 | − 0.522373537 | 0.00739 | |
| hsa-miR-548n | − 0.478327813 | 0.015578 | ||
| hsa-miR-100-5p | − 0.455529662 | 0.022119 | ||
| hsa-miR-455-5p | − 0.447259358 | 0.024981 | ||
| hsa-miR-378e | − 0.382669327 | 0.059029 | ||
| hsa-miR-627-3p | − 0.381315756 | 0.060007 | ||
| hsa-miR-1305 | − 0.379140547 | 0.061605 | ||
| hsa-miR-31-5p | − 0.362001741 | 0.075369 | ||
| hsa-miR-6511a-3p | − 0.357544996 | 0.079304 | ||
| hsa-miR-520a-5p | − 0.338430646 | 0.097972 | ||
| hsa-miR-539-5p | 0.40118042 | 0.046856 | ||
| hsa-miR-331-5p | 0.402409074 | 0.046124 | ||
| hsa-miR-548al | 0.407435901 | 0.043221 | ||
| hsa-miR-363-5p | 0.422764289 | 0.03525 | ||
| hsa-miR-6721-5p | 0.426606495 | 0.033448 | ||
| hsa-miR-199a-3p + hsa-miR-199b-3p | 0.443111451 | 0.026525 | ||
| hsa-miR-891b | 0.46766435 | 0.018406 | ||
| hsa-miR-1233-3p | 0.488245573 | 0.013278 | ||
| hsa-miR-33a-5p | 0.501372388 | 0.010672 | ||
| hsa-miR-499a-5p | 0.681817469 | 0.000174 |
IFTA interstitial fibrosis and tubular atrophy.