Table 4.

Multivariable analysis results (vs. main analysis).

	Main analysis SMD (95%CI)	Multivariable SMD (95%CI)
Age at PD onset	0.21 (0.12, 0.31)^a	0.27 (0.14, 0.4)^a
PD duration	0.34 (0.11, 0.57)^a	0.38 (0.26, 0.5)^a
Geriatric Depression Scale	0.32 (0.21, 0.42) ^a	0.49 (0.34, 0.64)^a
LEDD	0.54 (0.32, 0.77)^a	0.48 (0.35, 0.62)^a
MDS-UPDRS part 3^b	0.50 (0.34, 0.65)^a	0.51 (0.38, 0.65)^a
MOCA	−0.21 (−0.35, −0.08)^a	−0.17 (−0.31, −0.04)^a
State-Trait Anxiety Inventory	0.22 (0.11, 0.33)^a	0.4 (0.25, 0.55)^a

^ap < 0.05.

^bWe included all MDS-UPDRS part 3 (OFF, ON and unknown).