FIG. 8.

dDP mutant cells have a severe proliferative disadvantage. Clones of dDP mutant cells were induced at the first-instar larval stage by mitotic recombination. Examples of the clones observed in the eye (A) and wing (B) imaginal disks are presented. Homozygous mutant clones were visualized by the absence of GFP, while homozygous wild-type twin spots (+/+ in panel B) show a doubled GFP signal on a heterozygous background. (C) Clones were induced as described for panel B, wing imaginal disks were dissected and fixed at the early third-instar larval stage, and the sizes of the mutant clones and the corresponding twin spots were determined. The bars are ordered according to the size of the wild-type twin spots. Values for average clone areas of dDP mutant cells are indicated.