Table 2.
Kinetic parameters for the wild-type CotA and Q441A using AFB1 as substrate.
| Laccase | Km (mM)a | kcat (s−1) | kcat/Km (s−1 mM−1) |
|---|---|---|---|
| WT | 0.131 ± 0.004 | 0.054 ± 0.008 | 0.412 |
| Q441A | 0.084 ± 0.002 | 0.060 ± 0.005 | 0.714 |
Laccase activity was calculated at 37°C with 100 mM sodium phosphate buffer (pH 8.0). AFB1 was chosen as substrate. Km and kcat were determined by Michaelis-Menten equation.