TABLE 2.
Echocardiographic measurements under basal conditionsa
| Measurement | PINCH1flox/flox (n = 7) | PINCH1flox/flox Cre+/− (n = 9) |
|---|---|---|
| BW (g) | 28.1 ± 4.38 | 30.0 ± 5.27 |
| HR (bpm) | 511.6 ± 46.32 | 471.8 ± 101.7 |
| LVEDD (mm) | 3.48 ± 0.38 | 3.71 ± 0.75 |
| LVESD (mm) | 2.00 ± 0.42 | 2.25 ± 0.65 |
| PWth (mm) | 0.63 ± 0.05 | 0.60 ± 0.03 |
| IVSth (mm) | 0.64 ± 0.05 | 0.61 ± 0.04 |
| LV%FS | 43.05 ± 6.31 | 40.01 ± 6.76 |
| Vcf (circ/s) | 8.98 ± 1.70 | 8.42 ± 2.14 |
a
All data are presented as means ± standard errors. BW, body weight; HR, heart rate; LVEDD, end-diastolic left ventricular dimension; LVESD, end-systolic left ventricular dimension; PWth, left ventricular posterior wall thickness; IVSth, interventricular wall thickness; LV%FS, left ventricular percent fractional shortening; Vcf, velocity of circumferential fiber shortening. bpm, beats per minute; circ, circumference.