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. 2023 Nov 7;26(12):108407. doi: 10.1016/j.isci.2023.108407

Figure 1.

Figure 1

Composition of the complete dataset used in this study

We examined a total of 6,465 independent mutations in the lacZ gene to establish the importance of different amino acid residues in the function of β-gal. A wide variety of sequenced mutants induced by chemical or radiation exposure, different genetic backgrounds, and spontaneous mutants were compiled into the single dataset used in this study. Data from Beal et al. 2020.