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. 2023 Nov 7;26(12):108409. doi: 10.1016/j.isci.2023.108409

Figure 3.

Figure 3

B1KO females have higher fasting insulinemia at the end of pregnancy

Consequence of B1R deficiency on gestational metabolism at gestational day 16.5 (GD16.5) and 18.5 (GD18.5): fasting glycemia (A) and glucose tolerance test at GD16.5 (B), serum insulin level 30 min after glucose gavage (C); fasting insulin (D), blood glucose (E), cholesterol (F), triglycerides (G), and ketone bodies (H) levels at GD18.5. Maternal B1R deficiency increases fasting insulin levels at GD18.5 (p = 0.016). ∗p < 0.05. Data were compared by two-way ANOVA with Sidak’s multiple comparison test (B), Mann-Whitney (A, C, D, F, and G), and Student’s unpaired t test (E and H) at GraphPad Prism 7. Values expressed as mean ± SD of 3–11 mice per group. AUC – area under the curve. Blue = WT dam; Red = B1KO dam. See also Figure S1.