Fig. 2.

Development of cuproptosis associated lncRNAs predictive signature. (A) Forrest plot showing 10 prognostic cuproptosis-related lncRNAs by Univariable Cox regression analyses. (B) Correlations between cuproptosis regulators and the 3 model lncRNAs. (C) Bar plot reflecting the expression of signature lncRNAs in TCGA and GTEx database. (D) Survival time and status in the low- and high-risk groups in the training set. (E) ROC curves at 1, 3 and 5 years are described for the training set. (F) Survival analysis shows that survival outcomes are significantly different between low- and high-risk sufferers in training set. (G) Clinical ROC curves showing the prediction reliability between the risk score and other single clinical feature at one year. ROC curve, receiver operating characteristics curve; AUC, area under the curve. (***P < 0.001; **P < 0.01; *P < 0.05; ns, not statistically significant).