Table 2.
Comparison of the clinical features of the surgical safety group and liver dysfunction group (mean ± SD)
| Variables | Total |
Postoperative liver function
|
P value | |
|
No liver dysfunction
|
Liver dysfunction
|
|||
| Sex | ||||
| Male | 19 | 12 | 7 | 1.000 |
| Female | 16 | 11 | 5 | |
| Age (yr) | ||||
| < 60 | 20 | 14 | 6 | 0.721 |
| ≥ 60 | 15 | 9 | 6 | |
| BMI | ||||
| < 24 kg/m2 | 21 | 13 | 8 | 0.721 |
| > 24 kg/m2 | 14 | 10 | 4 | |
| BSA (m2) | 1.71 ± 0.18 | 1.75 ± 0.16 | 0.514 | |
| WBC (× 109/L) | 5.51 ± 2.39 | 5.19 ± 1.55 | 0.672 | |
| RBC (1012/L) | 4.30 ± 0.65 | 4.61 ± 0.44 | 0.146 | |
| PLT (× 109/L) | 126.17 ± 53.74 | 149.33 ± 79.83 | 0.314 | |
| ALB (g/L) | 40.71 ± 4.23 | 39.63 ± 4.18 | 0.478 | |
| Scr (μmol/L) | 76.98 ± 39.07 | 64.87 ± 10.63 | 0.303 | |
| ALT [U/L, M (QR)] | 67.26 ± 94.41 | 46.58 ± 30.40 | 0.468 | |
| AST [U/L, M (QR)] | 45.61 ± 23.63 | 58.00 ± 68.68 | 0.436 | |
| TB [umol/L, M (QR)] | 15.63 ± 7.20 | 20.99 ± 8.36 | 0.056 | |
| GGT [U/L, M (QR)] | 115.17 ± 112.78 | 124.00 ± 145.78 | 0.844 | |
| AFP [ng/mL, M (QR)] | 9999.23 ± 25773.40 | 8545.66 ± 15372.77 | 0.859 | |
| PIVKA-II [μg/L, M (QR)] | 1799.54 ± 5017.78 | 3574.73 ± 6543.79 | 0.378 | |
| PT (s) | 12.59 ± 1.46 | 12.39 ± 1.04 | 0.682 | |
| INR (s) | 1.10 ± 0.12 | 1.05 ± 0.11 | 0.227 | |
| LSM value (kPa) | 20.34 ± 4.89 | 25.78 ± 5.38 | 0.005a | |
| ICG R15 (%) | 7.99 ± 5.13 | 11.96 ± 6.43 | 0.055 | |
| SRLV (L/m2) | 0.349 ± 0.075 | 0.276 ± 0.036 | 0.003a | |
| Tumor-localizing | ||||
| Left half liver | 15 | 10 | 5 | 1.000 |
| Right half liver | 20 | 13 | 7 | |
| Tumor diameter [cm, M (QR)] | 6.63 ± 3.86 | 7.81 ± 4.91 | 0.436 | |
| Time of hepatic portal occlusion [min, M (QR)] | 14.65 ± 19.42 | 15.75 ± 14.10 | 0.864 | |
| Intraoperative bleeding [mL, M (QR)] | 908.70 ± 818.76 | 1541.67 ± 1612.57 | 0.130 | |
| Operation time (min) | 176.30 ± 49.98 | 185.83 ± 72.89 | 0.651 | |
a
P < 0.01 vs group of safe operation (no liver dysfunction) and liver dysfunction. PIVKA-II was abnormal prothrombin. BMI: Body mass index; BSA: Body surface area; WBC: White blood cell; RBC: Red blood cell; PLT: Platelet; ALB: Albumin; ALT: Alanine aminotransferase; AST: Aspartate aminotransferase; TB: Total bilirubin; GGT: γ-glutamyl transpeptidase; AFP: Alpha fetoprotein; PT: Prothrombin time; INR: International normalized ratio; LSM: Liver stiffness measure; ICG: Indocyanine green; SRLV: Standard residual liver volume.