Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
A model to explain the stimulation of MRTF activity by STARS. STARS binds to actin and promotes actin polymerization in the presence of basal Rho activity, which releases MRTFs from the inhibitory influence of G-actin, allowing the nuclear import of MRTFs and stimulation of SRF activity. SRF activates actin genes, which allows a negative-feedback loop.
