Table 2:
Characteristics of controlled clinical trials that compare technical variations of the same procedure.
| AUTHOR | COMPARE | PATIENTS | MESUREMENT | TECHNIQUE | CONCLUSION |
|---|---|---|---|---|---|
| Ugur et al. 2007 (Turkey) | PER-CPB with two needles vs one needle with 2 stylets | Pain due to Pca | Number of punctures and fluoroscopy injection time | L1 Posterior access, F-guide, 21G needle, Bu 0.5% 15 ml, OH 50% 10 ml | The use of a single needle may be a more effective and appropriate method for beginners or practitioners of other specialties. |
| LeBlanc et al. 2011 (EEUU) |
EUS-CPB with one vs two needles | Pain due to PCa. Age 63 years. Male 48% | Pain, duration of remission, complications | US-Guide, injection at the level of the celiac trunk of 20 ml of Bu 0.75% + 10 ml of OH 98% | No difference was found in pain relief or safety of the procedure |
| LeBlanc et al. 2013 (EEUU) |
EUS-CPB using 10 vs 20 ml of OH | Inoperable PCa pain. Age 66 years +/- 14. Male 55% | Pain and quality of life and security. | US-guide, access to the posterior wall of the stomach, needle 22G, Bu 0.75% 20 ml and then OH 98% | Both alternatives are safe with similar results, but more research is needed. |
| Dolly et al. 2016 (India) |
PER-CPB using 20, 30 and 40 ml of OH | Gallbladder cancer pain. Age 25-70 years. Male 20% | Pain (VAS), quality of life, morphine consumption, adverse effects | Lateral access intervertebral disc (T12), F-guide, 25G needle, 2% lidocaine, 2 ml contrast, 70% OH | The use of 40 ml was more effective in celiac plexus neurolysis |
| Abdelghaffar et al. 2019 (Egypt) |
PER-CPB with one vs two needles | Abdominal cancer pain | Blockage failure, procedure time, pain (VAS), rescues, and complications | Antecrural posterior access, T-guide, phenol 10% 25 ml in total | The use of a single needle with change of position had a lower failure rate and shorter procedure time, with no difference in complications or pain relief |
| Saeed et al. 2019 (Pakistan) | PER-CPB using OH 50 and 100% | Inoperable PCa pain. Age 57 years +/- 12. Male 54% | Pain (VAS, PainScale), complications | Posterior access to body level L1, F-guide, lidocaine 2%, OH 15 ml | Complications (back pain, diarrhoea or hypotension) were more frequent with 100% alcohol. Pain control was similar. |
PER-CPB: Percutaneous Celiac plexus block, EUS-CPB: Endoscopic-ultrasound Celiac plexus block, PCa: Pancreas cancer, F: Fluoroscopic, T: Tomographic, US: Ultrasonographic, Bu: Bupivacaine, OH: Alcohol.