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. 2023 Nov 21;36:101582. doi: 10.1016/j.bbrep.2023.101582

Table 1.

Micromorphological quantitative assay of liver sections.

Experimental Groups N = 6 Hydropic Degenerationa (Mean %)b Fatty Degenerationa (Mean %)b Vascular Congestiona (Mean %)b Inflammatory Cellsa (Mean %)b Lesion Scoring (0–100 %) Lesion Grading
(G1) NCGc 5.37 %A# 3.21 %A 6.42 %A 2.81 %A# 0–10 % No lesion
(G2) PCG (DOX) 92.78 %E 84.39 %E 79.62 %E 76.48 %E 75–100 % Critical
(G3) BZF + DOX 75.61 %D 69.56 %D 70.85 %D 74.55 %D 50–75 % Severe
(G4) GKB + DOX 71.64 %D 70.94 %D 74.61 %D 62.56 %D 50–75 % Severe
(G5) BZF + GKB + DOX 50.69 %C 49.72 %C 53.82 %C 48.51 %C 25–50 % Moderate

Notes.

#Statistical comparison among groups: Mean values with different capital letters have significant differences at (P < 0.05).

a

Hepatocytes hydropic degeneration, fatty degeneration and inflammatory cells were estimated in (%) of cell numbers. Area of vascular congestion estimated in mean percentage of (μm).

b

Each value represents the mean percentage (n = 6).

c

G1: Negative control group (NCG), Distilled water; G2: Positive control group (PCG), Doxorubicin (DOX) 3.6 mg/kg; G3: Bezafibrate (BZF) group 100 mg/kg with DOX; G4: Ginkgo biloba (GKB) group 60 mg/kg with DOX; G5: Bezafibrate 100 mg/kg and Ginkgo biloba 60 mg/kg with DOX.