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. Author manuscript; available in PMC: 2024 Feb 1.
Published in final edited form as: Pediatrics. 2023 Feb 1;151(2):e2022057865. doi: 10.1542/peds.2022-057865

Table 2.

Bivariate analysis of infant and hospital factors with HRIF participation

Not seen in HRIF (N=10790) Seen in HRIF (N=8721)
Number or mean Percent or Standard Deviation Number or mean Percent or Standard Deviation p-value
Maternal Race
 White 4877 45.2% 4600 52.8% <0.001
 Black 3759 34.8% 2587 29.7%
 Hispanic 1557 14.4% 1118 12.8%
 Asian 339 3.1% 300 3.4%
 Native American 95 0.9% 52 0.6%
 Other 155 1.4% 64 0.7%
Infant factors
Gestational age (weeks) 26.3 (1.9) 26.0 (1.8) <0.001
SGA (<10%ile) 1691 15.7% 1316 15.1% 0.27
Male 5543 51.4% 4417 50.7% 0.29
Multiple gestation 2499 23.2% 2354 27.0% <0.001
Inborn 8439 78.2% 7362 84.5% <0.001
Presence of NICU co-morbidity
IVH grade 3–4 1035 9.6% 797 9.1% 0.24
Periventricular leukomalacia 417 3.9% 338 3.9% 0.98
Bronchopulmonary Dysplasia 4748 44.0% 4116 47.2% 0.001
Necrotizing enterocolitis 737 6.8% 536 6.2% 0.052
Necrotizing enterocolitis requiring surgery 579 5.4% 419 4.8% 0.074
Focal intestinal perforation 443 4.1% 353 4.1% 0.83
Severe ROP 1357 13.1% 1290 15.1% <0.001
PDA requiring surgical ligation 1615 15.0% 1522 17.5% <0.001
Need for durable medical equipment at discharge
Gastrostomy or Jejunostomy tube 723 3.7% 551 6.3% 0.27
Home oxygen 2754 28.7% 2351 28.6% 0.96
Tracheostomy/Tracheotomy 199 1.9% 137 1.6% 0.14
Apnea/Cardiorespiratory monitoring 3747 39.0% 3580 43.6% <0.001
Hospital factors (N=58)
Hospital type
 Government-Owned 864 8.0% 945 10.8% 0.33
 Non-Profit 7955 73.7% 6938 79.6%
 Private 1303 12.1% 490 5.6%
 Other 663 6.1% 339 3.9%
Academic Hospital 7296 67.6% 6215 71.3% 0.63
Number of ELBW admissions annually
 Lowest Quintile (Q1) 529 4.9% 545 6.3% 0.76
 Middle Quintiles (Q2-Q4) 6996 64.8% 5176 59.4%
 Highest Quintile (Q5) 3266 30.3% 2991 34.3%
% White ELBW admissions
 Lowest Quintile (Q1) 1973 18.3% 1064 12.2% 0.092
 Middle Quintiles (Q2-Q4) 2693 25.0% 5915 67.9%
 Highest Quintile (Q5) 1419 13.2% 1733 19.9%

p-value for maternal race, infant factors, presence of NICU co-morbidity, and need for durable equipment at discharge computed using Chi square test or Student’s t test for categorical or continuous variables respectively. P-value for hospital factors computed using generalized linear models accounting for hospital-level clustering