Table 4. PPSS and its correlation with treatment selection and post-treatment outcomes.
PPSS (n= 12) | p | ||
Variable | Intermediate risk (2, 5) (2, 16.7%) | High risk (>5) (10, 83.3%) | |
Time of presentation <24 hours >24 hours |
1 (50%) 1 (50%) |
1 (10%) 9 (90%) |
0.165 |
Primary intervention(s) Surgery ± other interventions Endoscopic alone Radiological alone Endoscopic & Radiological |
0 (0%) 0 (0%) 2 (100%) 0 (0%) |
7 (70%) 0 (0%) 0 (0%) 3 (30%) |
- |
Re-intervention requirement3 Yes No |
1 (50%) 1 (50%) |
4 (40%) 6 (60%) |
- |
Post-procedure morbidityb Yes No |
1 (50%) 1 (50%) |
7 (70%) 3 (30%) |
0.583 |
Need for ICU stay Yes No |
2 (100%) 0 (0%) |
8 (80%) 2 (20%) |
0.488 |
Median LoHS, days | 24.5 | 26 | - |
Mortality 90-day In-hospital |
0% (0%) 0% (0%) |
0 (0%) 1 (10%) |
- |
PPSS: Pittsburgh severity score, ICU: Intensive care unit, LoHS: Length of hospital stay. a: Includes the patient in whom a re-intervention was warranted (stenting for persistent esophago-pleural fistula) but refused. b: Post-procedure morbidity includes re-interventions also. PPSS was calculated by assigning points to each clinical variable to a total score of 18 and three patient risk categories were identified (low risk <2, intermediate risk 2-5, high risk >5): 1 = age >75 years, heart rate >100 beats per minute, white cell count >10 x 109/mL, pleural effusion; 2= fever (>38.5 °C), uncontained leak (radiological studies), respiratory compromise (respiratory rate >30 per minute, need for increasing oxygen or mechanical ventilation), time of diagnosis >24 h; 3= oesophageal cancer, hypotension (17,18). |