Table 1.
Patient and tumor characteristics for cohort II (n=18,633).
|
|
All patients | Node negative (n=14,829) | Node positive (n=3804) | |
| Age (years), median (range) | 65 (22-95) | 65 (22-95) | 63 (23-94) | |
| Menopausal status, n (%) | ||||
|
|
Premenopausal | 3336 (19) | 2515 (18.04) | 821 (22.9) |
|
|
Postmenopausal | 14,224 (81) | 11,457 (81.96) | 2767 (77.12) |
|
|
Missinga | 1073 (5.76) | 857 (5.8) | 216 (5.7) |
| Mode of detection, n (%) | ||||
|
|
Mammographic screening | 10,816 (58.17) | 8992 (60.78) | 1824 (48.01) |
|
|
Symptomatic presentation | 7777 (41.83) | 5802 (39.22) | 1975 (51.99) |
|
|
Missing | 40 (0) | 35 (0) | 5 (0) |
| Tumor size (mm), median (range) | 15 (1-50) | 14 (1-50) | 19 (1-50) | |
| Multifocality, n (%) | ||||
|
|
Absent | 15,537 (83.54) | 12,730 (85.98) | 2807 (74) |
|
|
Present | 3061 (16.46) | 2075 (14.02) | 986 (26) |
|
|
Missing | 35 (0) | 24 (0) | 11 (0) |
| Histological type, n (%) | ||||
|
|
No special type | 14,322 (76.86) | 11,325 (76.37) | 2997 (78.79) |
|
|
Lobular | 2387 (12.81) | 1862 (12.56) | 525 (13.8) |
|
|
Other invasive, including mixed types | 1924 (10.33) | 1642 (11.07) | 282 (7.4) |
| Nottingham histological grade, n (%) | ||||
|
|
1 | 4112 (22.32) | 3600 (24.57) | 512 (13.6) |
|
|
2 | 9672 (52.49) | 7595 (51.83) | 2077 (55.03) |
|
|
3 | 4643 (25.2) | 3458 (23.6) | 1185 (31.4) |
|
|
Missing | 206 (1.1) | 176 (1.2) | 30 (1) |
| Estrogen receptor status, n (%) | ||||
|
|
Negative (<1%) | 1490 (8.32) | 1199 (8.41) | 291 (7.9) |
|
|
Positive (≥1%) | 16,423 (91.68) | 13,053 (91.59) | 3370 (92.05) |
|
|
Missing | 720 (3.9) | 577 (3.9) | 143 (3.8) |
| Progesterone receptor status, n (%) | ||||
|
|
Negative (<1%) | 2672 (15.14) | 2182 (15.56) | 490 (13.5) |
|
|
Positive (≥1%) | 14,973 (84.86) | 11,839 (84.44) | 3134 (86.48) |
|
|
Missing | 988 (5.3) | 808 (5.4) | 180 (4.7) |
| Human epidermal growth factor receptor 2 status, n (%) | ||||
|
|
Negative | 16,288 (88.67) | 12,989 (88.87) | 3299 (87.88) |
|
|
Positive | 2082 (11.33) | 1627 (11.13) | 455 (12.1) |
|
|
Missing | 263 (1.4) | 213 (1.4) | 50 (1) |
| Ki67 (%) | ||||
|
|
Values, median (range) | 20 (0-100) | 20 (0-100) | 24 (1-100) |
|
|
Missing, n (%) | 133 (0.7) | 123 (0.8) | 10 (0) |
aThe number of missing values is shown for noncomplete case variables.