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. 2023 Dec 5;5(4):zcad057. doi: 10.1093/narcan/zcad057

Figure 5.

Figure 5.

Low DDB2 levels predict better survival of oxaliplatin-treated colon cancer patients. Kaplan–Meier analysis shows association of tumor DDB2 mRNA levels with overall survival in (A)108 colon cancer TCGA patients clinically treated with oxaliplatin, (B) a subset of 87 patients diagnosed with colon cancer at TNM stage III and IV and clinically treated with oxaliplatin, and (C) a different group of 38 colon cancer patients clinically treated with regimens not containing oxaliplatin. (D) Kaplan-Meier analysis of association of tumor DDB2 expression levels with overall survival of patients diagnosed with cisplatin-treated cancers including lung cancer, (E) cervical cancer and (F) ovarian cancer. Each graph shows the mRNA level cut off leading to the best separation of the groups, the number of patients in each group and the P-value obtained in the logrank test.