Table 1. Modulation of Cytokine Secretion Profiles in Allergen-Stimulated PBMCs following PIT.

^a Cytokine concentration in picograms per millilitre with background (cells cultured in medium alone) subtracted

^b Patients from Group 1

^cND indicates not detected, and assigned a value of zero for statistical analysis. The sensitivity of the assays was 2.4 pg/ml for IL-5, 2.8 pg/ml for IL-10, and 7.1 pg/ml for IFN-γ

^d IFN-γ and IL-10 analysed with paired t-test (normal distribution), IL-5 analysed by Wilcoxon (non-normal distribution). Normality determined by Shapiro-Wilks test