Table 1.
Data sources for circulating proteins, obesity measures, lifestyle factors, and coronary artery disease
| Trait | Participants | Ancestry | Unit | PMID |
|---|---|---|---|---|
| Circulating protein | 35,559 individuals | European | SD | 34857953 |
| CAD (Consortia) | 60,801 cases; 123,504 controls | ~80% European | Odds ratio | 26343387 |
| CAD (FinnGen) | 39,036 cases; 303,463 controls | European | Odds ratio | / |
| Body mass index | 806,834 individuals | European | SD (~ 4.8 kg/m2) | 30239722 |
| Waist-to-hip ratio | 806,834 individuals | European | SD | 30239722 |
| Visceral adipose tissue | 325,153 individuals | European | 1 kg | 31501611 |
| Waist circumference | 224,459 individuals | European | SD | 25673412 |
| Smoking initiation | 1,232,091 individuals | European | SD in prevalence of smoking initiation | 30643251 |
| Lifetime smoking index | 462,690 individuals | European | SD change of lifetime smoking index | 31689377 |
| Alcohol drinking | 941,280 individuals | European | SD increase of log-transformed alcoholic drinks/week | 30643251 |
| Alcohol dependence | 46,568 individuals | European | SD in the prevalence of alcohol dependence | 30482948 |
| Coffee consumption | 375,833 individuals | European | 50% change | 31046077 |
| Caffeine consumption | 9876 individuals | European | 80 mg increase (equivalent to dose from 1 cup of coffee) | 27702941 |
| Sports | 124,842 cases; 225,650 controls | European | ≥ 2–3 versus 0 day/week | 29899525 |
| MVPA | 661,399 individuals | European | “Active” versus “inactive” (≥ 20 mins/week) | 36071172 |
| VPA | 98,060 cases; 162,995 controls | European | ≥ 3 versus 0 day/week | 29899525 |
| Sedentary behavior | 408,815 individuals | European | SD (~1.5 h) change of leisure television watching time | 32317632 |
| Leisure screen time | 661,399 individuals | European | SD (hours/day) | 36071172 |
| Sleep duration | 446,118 individuals | European | 60 min | 30846698 |
| Insomnia | 397,959 cases; 933,057 controls | European | SD in the prevalence of insomnia | 30804565 |
Abbreviations: CAD Coronary artery disease, MVPA Mzoderate to vigorous physical activity, SD Standard deviation, VPA Vigorous physical activity