Table 2.
Unadjusted associations between baseline characteristics and incident of elevated liver stiffness
| Variable | Statistics | Odds ratio (95% CIs) | P value |
|---|---|---|---|
| Age, years | 47.97 ± 12.59 | 1.04 (1.02, 1.05) | < 0.0001 |
| Sex, n (%) | |||
| Male | 3662 (63.24%) | 1.0 | |
| Female | 2129 (36.76%) | 0.47 (0.34, 0.64) | < 0.0001 |
| CHD, n (%) | |||
| No | 4216 (98.07%) | 1.0 | |
| Yes | 83 (1.93%) | 2.80 (1.38, 5.67) | 0.0045 |
| Diabetes, n (%) | |||
| No | 4119 (95.81%) | 1.0 | |
| Yes | 180 (4.19%) | 3.19 (1.97, 5.15) | < 0.0001 |
| Hypertension, n (%) | |||
| No | 3710 (86.30%) | 1.0 | |
| Yes | 589 (13.70%) | 2.46 (1.75, 3.44) | < 0.0001 |
| MAP, mmHg | 92.16 ± 13.26 | 1.04 (1.03, 1.05) | < 0.0001 |
| ALT, U/L | 26.02 ± 26.36 | 1.02 (1.02, 1.03) | < 0.0001 |
| AST, U/L | 24.44 ± 13.40 | 1.04 (1.04, 1.05) | < 0.0001 |
| FBG, mmol/L | 5.61 ± 1.27 | 1.29 (1.21, 1.36) | < 0.0001 |
| Creatinine, μmol/L | 71.32 ± 17.87 | 1.01 (1.00, 1.01) | 0.0149 |
| TG, mmol/L | 1.73 ± 1.35 | 1.19 (1.12, 1.26) | < 0.0001 |
| TC, mmol/L | 5.18 ± 1.03 | 1.05 (0.93, 1.19) | 0.4433 |
| HDL, mmol/L | 1.35 ± 0.33 | 0.28 (0.18, 0.45) | < 0.0001 |
| LDL, mmol/L | 3.16 ± 0.86 | 1.00 (0.86, 1.17) | 0.9827 |
Data are presented as mean ± SD, n (%), n/N (%), or median (IQR)
CHD coronary heart disease, MAP mean arterial pressure, ALT alanine transaminase, AST aspartate transaminase, FBG fasting blood–glucose, TG total triglyceride, TC total cholesterol, HDL high-density lipoprotein, LDL low-density lipoprotein