. 2023 Dec 5;23:117. doi: 10.1186/s40644-023-00633-z

Table 2.

Comparison of histogram parameters of diffusion metrics between soft and hard meningiomas

Histogram Parameters	Tumour Consistency		p Value
Histogram Parameters	Soft	Hard	p Value
ADC (×10^− 3 mm²/sec)
10th percentile	0.69 ± 0.09	0.60 ± 0.26	0.044 ^b *
90th percentile	0.91 ± 0.14	0.92 ± 0.42	0.324^b
Mean	0.82 ± 0.11	0.80 ± 0.22	0.982^b
Median	0.81 ± 0.11	0.78 ± 0.20	0.626^b
Kurtosis	7.19 ± 6.77	7.95 ± 4.88	0.492^b
Skewness	0.73 ± 0.95	0.97 ± 0.97	0.929^b
D (×10^− 3 mm²/sec)
10th percentile	0.49 ± 0.05	0.43 ± 0.22	0.054^b
90th percentile	0.61 ± 0.06	0.63 ± 0.13	0.358^b
Mean	0.55 ± 0.05	0.52 ± 0.12	0.432^a
Median	0.55 ± 0.05	0.55 ± 0.14	0.479^b
Kurtosis	5.13 ± 6.28	5.25 ± 6.15	0.808^b
Skewness	0.40 ± 0.89	0.35 ± 1.17	0.808^b
D* (×10^− 3 mm²/sec)
10th percentile	2.38 ± 0.77	1.64 ± 1.64	< 0.001 ^b **
90th percentile	6.17 ± 4.09	6.97 ± 5.11	0.288^b
Mean	4.20 ± 2.09	4.22 ± 2.15	0.859^b
Median	3.74 ± 1.85	3.52 ± 1.10	0.104^b
Kurtosis	38.08 ± 129.75	46.76 ± 54.62	0.674^b
Skewness	4.22 ± 5.16	4.71 ± 3.04	0.400^b
F
10th percentile	0.20 ± 0.04	0.19 ± 0.08	0.278^b
90th percentile	0.32 ± 0.08	0.33 ± 0.11	0.501^b
Mean	0.25 ± 0.06	0.28 ± 0.12	0.232^b
Median	0.25 ± 0.04	0.25 ± 0.10	0.912^b
Kurtosis	23.60 ± 40.09	7.06 ± 22.71	0.057^b
Skewness	2.92 ± 1.78	2.43 ± 2.07	0.391^a
Alpha
10th percentile	0.69 ± 0.09	0.64 ± 0.12	0.215^b
90th percentile	0.85 ± 0.05	0.93 ± 0.05	< 0.001 ^a **
Mean	0.77 ± 0.07	0.78 ± 0.07	0.084^b
Median	0.77 ± 0.07	0.80 ± 0.07	0.068^b
Kurtosis	3.90 ± 0.80	3.13 ± 1.46	0.073^b
Skewness	0.09 ± 0.47	0.31 ± 0.69	0.068^b
DDC (×10^− 3 mm²/sec)
10th percentile	0.68 ± 0.11	0.58 ± 0.37	0.020 ^b *
90th percentile	0.91 ± 0.20	0.93 ± 0.58	0.191^b
Mean	0.78 ± 0.17	0.78 ± 0.25	0.965^b
Median	0.77 ± 0.16	0.72 ± 0.16	0.113^b
Kurtosis	9.43 ± 13.35	11.29 ± 46.94	0.207^b
Skewness	1.19 ± 2.33	1.78 ± 4.63	0.199^b

Data are presented as the mean ± standard deviation (normalized distribution) or median ± interquartile range (skewness distribution) ADC, D, D*, and DDC are in units of ×10^− 3 mm²/sec

**p < 0.01, *p < 0.05

^a Comparisons were performed by independent samples t-test

^b Comparisons were performed by Mann‒Whitney U test