Table 1.
Demographic and clinical characteristics of patients
| Patient No |
Age [years] |
Sex | BW [kg] |
Primary disease |
Conditioning pretreatment | Type of HSCT |
RBC [× 104/μL] |
Hct [%] |
Hb [g/dL] |
Alb [g/dL] |
AST [U/L] |
ALT [U/L] |
T-bil [mg/dL] |
Cre [mg/dL] |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| #1 | 4.3 | M | 13.3 | CGD | ATG, BU, Flu, TBI | rPBSCT | 332 | 28.9 | 9.9 | 3.8 | 43 | 121 | 0.3 | 0.18 |
| #2 | 6.8 | F | 22.0 | BCP-ALL | Mel, TBI | CBT | 297 | 26.7 | 9.1 | 3.5 | 51 | 56 | 0.5 | 0.29 |
| #3 | 9.6 | F | 35.2 | AML | CY, TBI | CBT | 290 | 26.2 | 8.9 | 3.3 | 76 | 89 | 0.8 | 0.24 |
| #4 | 7.8 | M | 18.2 | AML | BU, Mel | rPBSCT | 312 | 32.5 | 10.7 | 2.6 | 113 | 150 | 0.5 | 0.23 |
| #5 | 6.8 | M | 29.8 | MDS | ATG, Flu, Mel, TBI | uBMT | 348 | 33.1 | 11.5 | 3.6 | 51 | 109 | 1.2 | 0.32 |
| #6 | 11.4 | F | 25.3 | T-ALL | CY, VP-16, TBI | uBMT | 287 | 28.2 | 9.6 | 2.4 | 96 | 95 | 3.5 | 0.24 |
| #7 | 2.3 | F | 11.3 | AML | BU, CY | CBT | 315 | 33.2 | 10.9 | 3.2 | 27 | 47 | 0.4 | 0.13 |
| #8 | 4.6 | M | 16.0 | BCP-ALL | CY, VP-16, TBI | CBT | 297 | 27.4 | 9.0 | 4.4 | 26 | 34 | 1.0 | 0.20 |
| #9 | 2.6 | F | 9.8 | EBV-LPD | Ara-C, Flu, Mel, MIT, VP-16, PSL | CBT | 334 | 28.5 | 10.1 | 3.5 | 18 | 13 | 3.3 | 0.21 |
| #10 | 0.7 | F | 7.3 | CAMT | ATG, Flu, Mel | CBT | 417 | 34.3 | 12.3 | 3.8 | 67 | 60 | 0.6 | 0.25 |
|
Median (range) |
5.7 (0.7–11.4) |
17.1 (7.3–35.2) |
314 (287–417) |
28.7 (26.2–34.3) |
10.0 (8.9–12.3) |
3.5 (2.4–4.4) |
51 (18–113) |
75 (13–150) |
0.7 (0.3–3.5) |
0.23 (0.13–0.32) |
M Male, F Female, BW Body weight, CGD Chronic granulomatous disease, BCP-ALL B-cell precursor acute lymphoblastic leukemia, AML Acute myeloid leukemia, MDS Myelodysplastic syndromes, T-ALL T-cell acute lymphoblastic leukemia, EBV-LPD Epstein-Barr virus-associated lymphoproliferative disease, CAMT Congenital amegakaryocytic thrombocytopenia, HSCT Hematopoietic stem cell transplantation, ATG Anti-thymocyte globulin, BU Busulfan, Flu Fludarabine, TBI Total body irradiation, Mel Melphalan, CY Cyclophosphamide, VP-16 Etoposide, Ara-C Cytarabine, MIT Mitoxantrone, PSL Prednisolone, rPBSCT Related peripheral blood stem cell transplantation, CBT Cord blood transplantation, uBMT Unrelated bone marrow transplantation, RBC Red blood cell, Hct Hematocrit, Hb Hemoglobin, Alb Albumin, AST Aspartate aminotransferase, ALT Alanine transferase, T-bil Total bilirubin, Cre Serum creatinine