Radiographic detection of prostate cancer metastases and histologic patterns. (A) Whole-body magnetic resonance imaging (MRI) showing suspected metastatic lesion in thoracic vertebra seven; metastasis to axial bones is most common in prostate cancer. Reproduced with permission from (Chen et al. 2021). (B) Metastatic bone biopsy demonstrating lytic, blastic, and mixed lesions within a single biopsy stained with Goldner-Masson trichrome. Green areas indicate bone, pink areas indicate prostate cancer, and red areas indicate osteoid. Ovals indicate differences among approximate bone volumes, including 70, 50, 20, and 2% (clockwise from bottom). Bar indicates 1 mm. Reproduced with permission from (Roudier et al. 2008).