Summary of the PTT enhancement by plasmonic nanosystems considering the cell line, AuNP shape and size, laser type, and uptake time.

Plasmonic nanosystem	Shape	Size (nm)	Laser type	Target cell	Uptake time	Ref.
CD44-antibody-PEG-AuNPs	Nanocages	58.4	CW 808 nm, 2.5 W cm−2	4T1 cells	24 h	124
Au-Ur@DTTC	Spherical	72.0	808 nm, 150 mW	SKOV3 and CT26 tumor	24 h	125
HAuNP@DTTC	Hollow sphere	85.0	808 nm	4T1 cells	24 h	126
MnO2@Au nanoenvelope	Spherical	150.0	808 nm, 0.25 W	PANC-1 and WI-38 cells	4 h	127
Ag@CuS NPs	Spherical	—	940 nm	HeLa cells	—	128
HA-4-ATP-AuNFs-DOX	Nanoframeworks	140.2 ± 3.2	1064 nm, NIR-II laser, 1 W cm−2	MDA-MB-231 breast cancer cells	2 h	129
AuNR-AS1411, AuNR-MUC1 (bioorthogonal SERS nanotags)	Nanorods	50.0 in length and 13.0 in width	808 nm, NIR laser, 0.2 W	MCF-7 breast cancer cells	4 h	130
Au@PB NPs	Spherical	72.0	808 nm laser, 2.0 W cm−2	4T1 mammary carcinoma cells	24 h	131
Nanoenvelope (ISQ@BSAAuNC@AuNR@DAC@DR5)	Nanorods	∼30.0 in length and ∼10.0 in width	808 nm	A375 human melanoma cells	—	132
Au nanostars (Au-4MBA-RGD)	Nanostars	295.4 ± 14.8	785 nm NIR-I laser, 390 mW cm−2, 1064 nm NIR-II laser, 1160 mW cm−2	A549 human lung adenocarcinoma cells	—	133
Aptamer-conjugated Au nanocage/SiO2	Regular cubic geometry	Outer edge length: ∼29, wall thickness: ∼3.5, slight corner truncation, and tiny pores on the side face	785 and 808 nm laser, 1.5 W cm−2	MCF-7 breast cancer cells	24 h	134
Au@Cu2−xS core–shell NPs	Hexagonal Cu2−xS (x = 1) (008) and face-centered cubic (fcc) Au	85.87 ± 10	808 nm laser, 0.45 W cm−2	HeLa cells and 4T1 cells	24 h	135
GNS-L/GB	Shells	85.0	808 nm laser, 4 W cm−2	MIA PaCa-2 and PANC-1 cells	48 h	136
Glu-AuNP	Sphere	16.0	X-radiation, 100 kVp, 10 Gy	MCF-7	2 h	137