Table I.

Histopathological and immunohistochemical scores of the groups

Group	Perivascular inflammation	Erythrocyte extravasation	Macrophage infiltration	Hemosiderin accumulation	MMP-2 staining
Control	0.0 (0.0–0.0)	0.0 (0.0–0.0)	0.0 (0.0–1.0)	0.0 (0.0–0.0)	0.0 (0.0–0.0)
Sham	0.0 (0.0–1.0)	0.5 (0.0–1.0)	0.5 (0.0–1.0)	0.0 (0.0–1.0)	0.0 (0.0–1.0)
CVH	2.5 (1.0–3.0)	3.0 (2.0–3.0)	3.0 (2.0–3.0)	1.0 (1.0–3.0)	2.0 (1.0–3.0)
P-value	< 0.001*	< 0.001*	< 0.001*	< 0.001*	< 0.001*

Data are presented as median (minimum–maximum);

^*p < 0.05. CVH – coronary venous hypertension, MMP-2 – matrix metalloproteinase-2.