Figure 1:

Algorithm for oseltamivir and zanamivir prophylaxis or early treatment in close contacts of suspected or laboratory-confirmed case.

This algorithm has been expanded from the original version as seen in Appendix D of the Use of Antiviral Drugs for Influenza: A Foundation Document for Practitioners to include emerging zoonotic influenza exposure events.

^* Table 3 as published in The Use of Antiviral Drugs for Influenza: A Foundation Document for Practitioners 2013 (16).

^† Presumptive treatment is therapy with twice daily doses of oseltamivir or zanamivir initiated before the onset of influenza symptoms in close contact of individuals with suspected or lab-confirmed influenza illness.

^‡ Early treatment is therapy with twice daily doses of oseltamivir or zanamivir initiated ideally within 48 hours of the onset of influenza symptoms.