. Author manuscript; available in PMC: 2024 Sep 20.

Published in final edited form as: Neuron. 2023 Jul 12;111(18):2811–2830.e8. doi: 10.1016/j.neuron.2023.06.008

Table 2.

Electrophysiological characterization of cultured neurons innervating the injured knee reveal unique cellular signatures that punctuate the pain progression at Day 3 and Day 10.

	Days post-injection
	Day 3		Day 10
	Contra (n = 40)	Ipsi (n = 42)	Contra (n = 48)	Ipsi (n = 57)
Resting membrane potential (mV)	−45.93 ± 0.88	−43.07 ± 1.18	−48.04 ± 1.18 ^***	−42.35 ± 1.00 ^***
Capacitance (pF)	38.72 ± 3.04	38.65 ± 3.43	40.23 ± 3.48	42.75 ± 3.18
Action potential amplitude (mV)	86.83 ± 2.74	78.73 ± 0.24	85.98 ± 3.03	85.15 ± 2.66
Half peak duration (ms)	2.29 ± 0.16	2.77 ± 0.24	2.19 ± 0.17	2.60 + 0.14
Afterhyperpolarization amplitude (mV)	15.66 ± 0.65	14.69 ± 0.68	14.63 ± 0.78	14.77 ± 0.77
Afterhyperpolarization duration (ms)	9.50 ± 0.66	8.17 ± 0.56	11.71 ± 1.20	12.17 ± 1.14

Intrinsic and active properties of knee innervating dorsal root ganglion neurons from the MIA injected side (Ipsi) and contralateral (Contra) side.

^***

p < 0.001, unpaired t-test.