KEY RESOURCES TABLE

REAGENT or RESOURCE	SOURCE	IDENTIFIER
Chemicals, peptides, and recombinant proteins
Caffeine	Sigma-Aldrich	C8960
Coumarin	Sigma-Aldrich	C4261
Decanoic acid	Sigma-Aldrich	C1875
Hexanoic acid	Sigma-Aldrich	153745
Indigocarmine	Sigma-Aldrich	18130
Lobeline	Sigma-Aldrich	141879
Sucrose	Sigma-Aldrich	S7903
Sulforhodamine	Sigma-Aldrich	230162
Tricholine citrate	Sigma-Aldrich	T0252
Octanoic acid	Sigma-Aldrich	C2875
Quinine	Sigma-Aldrich	22630
Deposited data
Original data and results of statistical analyses	This paper, Mendeley data	https://doi.org/10.17632/srrd35bxcm.1
Experimental models: Organisms/strains
D. melanogaster, Canton-S		N/A
D. sechellia	Drosophila Species Stock Center	14021-0248.25
D. simulans, w[501]	Drosophila Species Stock Center	14021-0251.195
D. melanogaster: Gr32a-GAL4	Bloomington Drosophila Stock Center	57622
D. melanogaster: Gr33a 1	Bloomington Drosophila Stock Center	31427
D. melanogaster: ΔGr64a-f	Dr. Seok Jun Moon’s laboratory49	N/A
D. melanogaster: Gr64f-GAL4	Bloomington Drosophila Stock Center	27883
D. melanogaster: Ir47a 1	This paper, Figure 6	N/A
D. melanogaster: Ir56d 1	Bloomington Drosophila Stock Center	81249
D. melanogaster: Ir76b 1	Bloomington Drosophila Stock Center	51309
D. melanogaster: orco 1	Bloomington Drosophila Stock Center	23129
D. melanogaster: UAS-Kir2.1	Bloomington Drosophila Stock Center	91802
D. melanogaster: vas-Cas9	Bloomington Drosophila Stock Center	51324
D. melanogaster: w 1118	Bloomington Drosophila Stock Center	5905
Oligonucleotides
5’-CTTCGAGCGACAGTAACATAACCG	Integrated DNA Technologies	N/A
5’-AAACCGGTTATGTTACTGTCGCTC	Integrated DNA Technologies	N/A
Recombinant DNA
pBS-U6-BbsI-chiRNA	Addgene	45946
pattB[U6-Ir47a-chiRNA]	This paper, Figure 6	N/A